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Know the Edge
TRUS Sports College Football Board

Know the Edge

Every AP Top 25 team, every ranked matchup and the TRUS Sports prediction for the September 25–26 slate.

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Texas running back Hollywood Smothers scoring against Ohio State
AP Top 25 Matchup BoardChecked Sep. 25 · 6:00 a.m. PT
No. 1 Texas at No. 14 Tennessee

Texas must survive Neyland’s first punch

Texas −4.5 · Total 54.5

Tennessee’s tempo and crowd can create an early swing, but Texas owns the deeper defensive answers and the cleaner path on late downs.

TRUS edgeTexas −4.5
TEX 31–24
Oklahoma at No. 2 Georgia

Defense keeps it tight—until Georgia leans

Georgia −13.5 · Total 44.5

Oklahoma can compress the game, but Georgia’s physical depth should create the deciding fourth-quarter possessions.

TRUS edgeGeorgia −13.5
UGA 27–13
No. 3 Notre Dame at Purdue

Irish pressure travels

Notre Dame −27.5 · Total 58.5

Notre Dame’s advantage in the trenches should shorten Purdue’s possessions and build separation before halftime.

TRUS edgeNotre Dame −27.5
ND 42–14
No. 4 Ole Miss at No. 21 Florida

The ranking says Ole Miss; the market says Florida

Florida −3.5 · Total 59.5

Ole Miss has the explosive quarterback play to answer Florida’s home-field pressure. Taking the points protects a true toss-up.

TRUS edgeOle Miss +3.5
MISS 31–30
Northwestern at No. 5 Indiana

Indiana’s pace creates the margin

Indiana −20.5 · Total 49.5

The Hoosiers can force Northwestern to chase points, where the underdog’s limited explosiveness becomes the central problem.

TRUS edgeIndiana −20.5
IND 35–13
Central Michigan at No. 6 Miami

A huge number demands discipline

Miami −41.5 · Total 54.5

Miami should control the game, but six touchdowns is a heavy tax once the rotation reaches the field.

TRUS edgeCentral Michigan +41.5
MIA 45–10
Illinois at No. 7 Ohio State

Ohio State controls without chasing style points

Ohio State −27.5 · Total 53.5

The Buckeyes’ defense can dominate the matchup, while a four-touchdown spread makes the total more attractive than the side.

TRUS edgeUnder 53.5
OSU 38–13
South Carolina at No. 8 Alabama

Alabama’s response starts up front

Alabama −12.5 · Total 54.5

South Carolina can create pressure, but Alabama’s offensive ceiling and home-field depth point to a two-touchdown result.

TRUS edgeAlabama −12.5
ALA 34–20
No. 23 Texas A&M at No. 10 LSU

LSU gets the rebound spot at night

LSU −9.5 · Total 51.5

Both teams need a response, but LSU’s passing-game ceiling and Tiger Stadium create the stronger recovery setup.

TRUS edgeLSU −9.5
LSU 31–20
Sam Houston at No. 11 Texas Tech

Texas Tech can turn volume into a runaway

Texas Tech −34.5 · Total 55.5

The Red Raiders’ scoring pace creates too many possessions for an overmatched visitor to protect the number.

TRUS edgeTexas Tech −34.5
TTU 45–10
No. 20 Oregon at No. 12 USC

The Coliseum turns into a track meet

Oregon −3 · Total 61.5

Both offenses can stress space, and neither side has shown enough defensive certainty to make three points feel safe.

TRUS edgeOver 61.5
ORE 34–31
Wisconsin at No. 13 Penn State

Penn State’s defense owns the leverage downs

Penn State −10 · Total 44.5

Wisconsin can keep the game physical, but Penn State has the better path to points when the field compresses.

TRUS edgePenn State −10
PSU 27–16
No. 15 Utah at Iowa State

Utah’s structure travels

Utah −7.5 · Total 47.5

Utah’s line play and defensive discipline should matter more as the game moves into second-and-long and third-and-medium.

TRUS edgeUtah −7.5
UTAH 27–17
Wake Forest at No. 16 Louisville

Louisville’s balance breaks the game open

Louisville −13.5 · Total 57.5

The Cardinals can win on the ground or through play action, forcing Wake Forest to defend the entire width of the field.

TRUS edgeLouisville −13.5
LOU 34–20
No. 17 Iowa at No. 18 Michigan

One mistake may decide the lowest total

Michigan −5.5 · Total 38.5

Both teams are built to shrink possessions. Iowa’s points are attractive, but the sharper TRUS angle is on a game played below 40.

TRUS edgeUnder 38.5
MICH 20–16
No. 19 Missouri at No. 24 Mississippi State

The underdog can stay inside the number

Mississippi State −6 · Total 58.5

Mississippi State’s home advantage is real, but Missouri has enough offense to prevent a full two-score separation.

TRUS edgeMissouri +6
MSST 31–27
Missouri State at No. 22 SMU

SMU’s speed decides it early

SMU −34.5 · Total 59.5

SMU’s loss at Louisville creates a focused bounce-back spot against a defense that will struggle to handle tempo and space.

TRUS edgeSMU −34.5
SMU 45–10
No. 25 Houston at Georgia Southern

The road favorite faces a dangerous number

Houston −17.5 · Total 56.5

Houston should win, but Georgia Southern’s home pace gives the underdog a route to remain within three scores.

TRUS edgeGeorgia Southern +17.5
HOU 34–20
No. 9 BYU

Bye week

No game this weekend. TRUS Sports will reset the Cougars’ edge when they return.

TRUS Sports note: These are editorial predictions, not guarantees. Lines can move; injuries, weather and availability should be rechecked before kickoff. The score projection explains the matchup view, while the “TRUS edge” identifies the preferred market angle at the listed number.